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Adenosine A3-R Polyclonal Antibody

Adenosine A3-R Polyclonal Antibody

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Specification

Product name Adenosine A3-R Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human Adenosine A3-R at AA range: 250-330
Host Rabbit
Reactivity Human
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative ADORA3; Adenosine receptor A3

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background ADORA3 encodes a protein (adenosine A3 receptor) that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. ADORA3 shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein.
Gene ID 140
Alternative ADORA3; Adenosine receptor A3
Others Adenosine A3-R Polyclonal Antibody detects endogenous levels of Adenosine A3-R protein.
Accession P33765

Image & description

Fig.1. Western Blot analysis of various cells using Adenosine A3-R Polyclonal Antibody.

Fig.1. Western Blot analysis of various cells using Adenosine A3-R Polyclonal Antibody.

Fig.2. Western Blot analysis of MCF7 cells using Adenosine A3-R Polyclonal Antibody.

Fig.2. Western Blot analysis of MCF7 cells using Adenosine A3-R Polyclonal Antibody.

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