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AChRα3 Polyclonal Antibody

AChRα3 Polyclonal Antibody

Views(556) Publications(0) Catalog no(ABP50583)
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Specification

Product name AChRα3 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human AChRα3
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CHRNA3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CHRNA3 encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. CHRNA3 encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein (cholinergic receptor nicotinic alpha 3 subunit) is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
Gene ID 1136
Alternative CHRNA3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3
Others AChRα3 Polyclonal Antibody detects endogenous levels of AChRα3 protein.
Accession P32297

Image & description

Fig. Western Blot analysis of various cells using AChRα3 Polyclonal Antibody.

Fig. Western Blot analysis of various cells using AChRα3 Polyclonal Antibody.

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