Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase in eukaryotic cells. It achieves this processivity by encircling the DNA, thus creating a topological link to the genome. PCNA was originally identified as an antigen that is expressed in the nuclei of cells during the DNA synthesis phase of the cell cycle.
Anti-PCNA Mouse Monoclonal Antibody (1D7) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, with reactivity including Human, Mouse and Rat.This antibody has been tested with IHC and WB applications. And Abbkine suggested starting dilutions are as follows: WB 1:5000, IHC-p 1:200.
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